Essential thrombocythemia – ClinCaseQuest https://clincasequest.hospital Medical education in clinical cases Fri, 14 Jan 2022 20:07:36 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.14 https://clincasequest.hospital/wp-content/uploads/sites/7/2020/02/logo-ru-project-90x90.png Essential thrombocythemia – ClinCaseQuest https://clincasequest.hospital 32 32 IPSET – Thrombosis Risk for essential thrombocythemia: Online Calculator https://clincasequest.hospital/ipset/ Thu, 13 Jan 2022 16:09:57 +0000 https://clincasequest.hospital/?p=32701 International Prognostic Score of thrombosis in World Health Organization – essential thrombocythemia (IPSET-thrombosis). IPSET-thrombosis model provides objective estimates of the probability of thrombotic events in…

Сообщение IPSET – Thrombosis Risk for essential thrombocythemia: Online Calculator появились сначала на ClinCaseQuest.

]]> International Prognostic Score of thrombosis in World Health Organization – essential thrombocythemia (IPSET-thrombosis).

IPSET-thrombosis model provides objective estimates of the probability of thrombotic events in patients with newly diagnosed ET.

Loading...

(one or more of: hypertension, diabetes mellitus, active smoking)

Points 0
* Required

The scale consist of the following parameters, listed below:

Patient age 
• under 60 years0
• 60 years or older1
Prior thrombotic event2
Cardiovascular risk factors present
(One or more of: hypertension, diabetes mellitus, active smoking)		1
Detected JAK2 V617F mutation2

The primary objective of essential thrombocythemia (ET) management is to prevent thromboembolic complications. In this regard, advanced age and thrombosis history were used to assess this risk. More recently, JAK2V617F and cardiovascular (CV) risk factors were identified as additional modifiers, leading to the development of a 3-tiered International Prognostic Score of Thrombosis for ET (IPSET-thrombosis): “low”, “intermediate”, and “high”.

Total 6 points (Age 1, H/O Thrombosis 2, Cardiovascular risk factor 1 and JAK2V617F – 2 points).

Determine risk group and prognosis:

ScoreRisk categoryAnnual thrombosis risk
0 – 1Low1.03%
2Intermediate2.35%
3 – 6High3.56%

Register on our website right now to have access to more learning materials!

Subscribe to our pages:

Reference:
Barbui T, Finazzi G, Carobbio A, Thiele J, Passamonti F, Rumi E et al. Development and validation of an International Prognostic Score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis). Blood 2012; 12: 5128-33

Сообщение IPSET – Thrombosis Risk for essential thrombocythemia: Online Calculator появились сначала на ClinCaseQuest.

]]>