IPSET – Thrombosis Risk for essential thrombocythemia: Online Calculator

International Prognostic Score of thrombosis in World Health Organization – essential thrombocythemia (IPSET-thrombosis).
IPSET-thrombosis model provides objective estimates of the probability of thrombotic events in patients with newly diagnosed ET.
The scale consist of the following parameters, listed below:
Patient age | |
• under 60 years | 0 |
• 60 years or older | 1 |
Prior thrombotic event | 2 |
Cardiovascular risk factors present (One or more of: hypertension, diabetes mellitus, active smoking) | 1 |
Detected JAK2 V617F mutation | 2 |
The primary objective of essential thrombocythemia (ET) management is to prevent thromboembolic complications. In this regard, advanced age and thrombosis history were used to assess this risk. More recently, JAK2V617F and cardiovascular (CV) risk factors were identified as additional modifiers, leading to the development of a 3-tiered International Prognostic Score of Thrombosis for ET (IPSET-thrombosis): “low”, “intermediate”, and “high”.
Total 6 points (Age 1, H/O Thrombosis 2, Cardiovascular risk factor 1 and JAK2V617F – 2 points).
Determine risk group and prognosis:
Score | Risk category | Annual thrombosis risk |
0 – 1 | Low | 1.03% |
2 | Intermediate | 2.35% |
3 – 6 | High | 3.56% |
Register on our website right now to have access to more learning materials!
Subscribe to our pages:
Checklist – Counseling “Explain a bone marrow aspiration”
IntroductionPointsIntroduces and identifies patient1Gains consent1Explore Checks patients understanding for reason for Bone Marrow Aspiration2Check’s patients understanding…
Checklist – Counseling “History of Acute Intermittent Porphyria”
IntroductionPointsIntroduce and check the details1Consent1Presenting Compliant Elicit intermittent nature of abdominal pain1Details on length of suffering…
Clinical Presentation Alzheimer Disease
Learning Objectives: 1. Discuss the differential diagnoses of dementia 2. Identify the clinical manifestations of…
Karnofsky Performance Status Scale Online Calculator
Karnofsky performance status scale determines ability of patient to tolerate chemotherapy. For patients ≥ 16…
Drug Resistance in Pneumonia (DRIP) Score. Online Calculator
The purpose of the DRIP score is to determine when broad-spectrum antibiotics should be used…
Calgary-Сambridge guide to the medical interview
This manual was developed by specialists from the Faculty of Medicine of the University of…