Hasford score: online calculator

Sokal, Hasford, and EUTOS scores were developed at different times in the treatment of chronic myeloid leukemia (CML). Hasford score is a prognostic score for survival of patients with chronic myeloid leukemia treated with interferon alfa. Interferon alfa is a conservative and widely used alternative to bone marrow transplantation in treatment of patients with early chronic myeloid leukemia before tyrosine kinase inhibitors implementation in clinical practice. 

Age:

Spleen size
Maximum distance palpable below costal margin:


Cm
Inches

Platelet count:

10⁹/L
10³/µL

Peripheral blood blasts (% of leukocytes):

Peripheral blood eosinophils (% of leukocytes):

Peripheral blood basophils (% of leukocytes):



Patient’s Hasford score Hasford score range Hasford risk group
0 0 0

0.666 when age ≥50 years + (0.042 x spleen) + 1.0956 when platelet count > 1500 x109/l + (0.0584 x blasts cells) + 0.20399 when basophils  > 3% + (0.0413 x eosinophils)x100

  • Age in years
  • Spleen is in cm below the costal margin
  • Blast cells, eosinophils and basophils are in percent of peripheral blood differential.

Hasford score

  • ≤ 780 – Low risk
  • 781-1480 – Intermediate risk
  • ≥1480 – High risk 

A source:
Hasford J, Pfirrmann M, Hehlmann R, Allan NC, Baccarani M, Kluin-Nelemans JC et al. A new prognostic score for survival of patients with chronic myeloid leukemia treated with interferon alfa. J Natl Cancer Inst. 1998; 90: 850-8.



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